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What is Cystinuria?
Very basically, cystinuria is a genetic defect in which the kidney is not able to process a basic amino acid, cystine, correctly. Affected dogs are born with this condition but in most cases it takes many years before things get bad enough that we notice it.

Over time, the unprocessed cystine in the urine clumps together to form stones. These stones can block the urinary tract. This is a life-threatening condition and requires surgery.

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New January 2010!
Dr. Paula Henthorn is conducting research into Canine Cystinuria at the University of Pennsylvania. The Mastiff Club of America Cystinuria Committee has issued an update on that research that contains some extremely promising news about a genetic test and tantalizing information that might help us make better decisions about our affected dogs. Read the update here.

My Dog Has Cystinuria:
What Do I Do Now?
People usually search for information on cystinuria because their dog was diagnosed with cystine stones, or tested positive for cystine in the urine on a screening test at the University of Pennsylvania.

If your dog tested positive on the screening test, he may or may not go on to form stones. One study suggests that as few as 1 in 6 dogs with cystinuria form stones. However, our knowledge of this condition is not complete enough to state the risk with certainty. You must watch your dog closely for signs of interrupted urinary flow, frequent urination, scanty urination, or blood in his urine, and react immediately if they are seen.

If your dog has already formed stones, you will be full of questions. Read More Here!

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